O a sex with sam
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While this effort has contributed to help better explain species tolerance and increase reliability of future change projections, intraspecific variation in OA responses has received insufficient attention, creating uncertainty in reported responses and their interpretation [ 6 ]. Do OA studies consider the impact of sex on organism responses? By incorporating the highly dynamic nature of carbonate chemistry in many natural systems [ 4 ], as well as multi-stressor interactions [ 5 ], and an ever-increasing range of organisms, life-history stages, communities and multiple generations [ 5 ], studies have also become increasingly complex. Identifying the sources and consequences of variability in biological responses is pivotal to understanding a population's ability to cope with environmental change [ 7 , 8 ]. Over the past 10 years, studies investigating the ecological effects of OA have increased exponentially [ 3 ]. Abstract Ocean acidification OA poses a major threat to marine ecosystems globally, having significant ecological and economic importance. However, despite recent evidence that many physiological, behavioural, immunological, molecular and neuro-toxicological functions are influenced by sex-based differences [ 9 , 10 ], and despite many of these same processes being impacted by elevated pCO2 [ 5 ], the overarching role of sex in determining response to OA remains understudied [ 11 ].
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